Gerstmann Syndrome

Gerstmann syndrome is a neurocognitive disorder characterized by a tetrad of agraphia, acalculia, finger agnosia, and left-right disorientation, usually resulting from lesions in the dominant inferior parietal lobule. Etiologies include stroke, trauma, tumors, and neurodegenerative disease. Pathophysiology involves disruption of parietal lobe cortical networks responsible for spatial and numerical processing. Diagnosis is clinical, supported by neuroimaging. Management focuses on rehabilitation and cognitive therapy; prognosis depends on lesion extent and underlying etiology.