Alien Hand Syndrome

Alien hand syndrome is a rare neurological disorder in which one hand acts involuntarily, independent of conscious control, often perceived as foreign by the patient. It arises from lesions involving the corpus callosum, frontal lobe, or parietal regions, commonly secondary to stroke, surgery, or neurodegeneration. Patients demonstrate involuntary grasping, groping, or intermanual conflict. Diagnosis relies on clinical observation and neuroimaging to identify underlying lesions. Management is largely rehabilitative, employing behavioral strategies and occupational therapy; prognosis depends on lesion etiology and extent.