Superficial Siderosis

Superficial siderosis is a rare neurodegenerative disorder caused by chronic subarachnoid hemorrhage and deposition of hemosiderin along the CNS surface. Clinical features include sensorineural hearing loss, cerebellar ataxia, and pyramidal signs. Pathophysiology involves oxidative neuronal injury from iron deposition. Diagnosis relies on MRI demonstrating hypointense hemosiderin deposition. Management is primarily supportive, with iron chelation or surgical repair of bleeding source in select cases; prognosis is slowly progressive.