Acute Flaccid Myelitis

AFM is a rare polio-like syndrome predominantly affecting children, characterized by sudden-onset asymmetric flaccid paralysis. Pathophysiology involves selective injury to anterior horn cells of the spinal cord, frequently following viral respiratory infections, particularly enteroviruses. MRI typically reveals lesions in spinal gray matter, and cerebrospinal fluid analysis may show mild pleocytosis. Management is supportive, focusing on physical rehabilitation and prevention of complications, as no specific antiviral therapy exists. Recovery is variable, with some patients regaining strength while others experience persistent motor deficits.